Seqanswers Leaderboard Ad

Collapse

Announcement

Collapse
No announcement yet.
X
 
  • Filter
  • Time
  • Show
Clear All
new posts

  • How to identify differentially expressed genes within a single sample group?

    What are the reasonable ways to identify differentially expressed genes within a Single sample group consisting of 5 replicates with RNA-seq data? There is no second or other group to compare.
    Appreciate your suggestions. Thank you.

  • #2
    Differentially expressed versus what?

    Comment


    • #3
      With differentially expressed genes, I meant to say genes that are over-expressed or under-expressed within a single experimental group consisting of more than one replicates. There is no second group or 'normal' group to compare the experimental group. For example, how to identify genes over- or under-expressed in tumor samples of a specific cancer type in the absence of 'normal' samples or any other possible secondary experimental group.

      Comment


      • #4
        But "differentially expressed" implies you compare group A with group B to find differences between the groups.

        Comment

        Latest Articles

        Collapse

        • seqadmin
          Latest Developments in Precision Medicine
          by seqadmin



          Technological advances have led to drastic improvements in the field of precision medicine, enabling more personalized approaches to treatment. This article explores four leading groups that are overcoming many of the challenges of genomic profiling and precision medicine through their innovative platforms and technologies.

          Somatic Genomics
          “We have such a tremendous amount of genetic diversity that exists within each of us, and not just between us as individuals,”...
          05-24-2024, 01:16 PM
        • seqadmin
          Recent Advances in Sequencing Analysis Tools
          by seqadmin


          The sequencing world is rapidly changing due to declining costs, enhanced accuracies, and the advent of newer, cutting-edge instruments. Equally important to these developments are improvements in sequencing analysis, a process that converts vast amounts of raw data into a comprehensible and meaningful form. This complex task requires expertise and the right analysis tools. In this article, we highlight the progress and innovation in sequencing analysis by reviewing several of the...
          05-06-2024, 07:48 AM

        ad_right_rmr

        Collapse

        News

        Collapse

        Topics Statistics Last Post
        Started by seqadmin, 05-24-2024, 07:15 AM
        0 responses
        16 views
        0 likes
        Last Post seqadmin  
        Started by seqadmin, 05-23-2024, 10:28 AM
        0 responses
        18 views
        0 likes
        Last Post seqadmin  
        Started by seqadmin, 05-23-2024, 07:35 AM
        0 responses
        22 views
        0 likes
        Last Post seqadmin  
        Started by seqadmin, 05-22-2024, 02:06 PM
        0 responses
        11 views
        0 likes
        Last Post seqadmin  
        Working...
        X