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  • *#1*
    Junior Member
    • Jul 2010
    • 8

    #1

    Non-commercial SNP calling soft

    I noticed that information on SNP calling and SNP discovery (especially!) software for NGS is quite scarce. Are there any good tools available from non-commercial sources? Could you suggest any titles (and corresponding URLs) one would want to look at? I am specifically looking for solutions for a robust secondary data analysis pipeline in a non-profit environment, for the data from virtually all platforms/read lengths, including 454, Illumina, SOLiD, and future platforms suich as PacBio, Ion Torrent, etc. Maybe we could start a list of such software here, with some details on which software is best for what kind of data. Thanks!
    Last edited by *#1*; 10-19-2010, 05:36 PM. Reason: typo
  • jgibbons1
    Senior Member
    • Oct 2009
    • 135

    #2
    I've found MAQ to be very good tool for SNP calling, but I'm not sure if it can handle larger reads. I use it with Illumina data.

    http://maq.sourceforge.net/maq-man.shtml

    Comment

    • nilshomer
      Nils Homer
      • Nov 2008
      • 1283

      #3
      See the Software Hub.

      Comment

      • Boel
        Member
        • Oct 2009
        • 62

        #4
        Gatk

        Check out the genome analysis tool kit (GATK) developed at the Broad:
        http://www.broadinstitute.org/gsa/wi...alysis_Toolkit

        The UnifiedGenotyper is one of the task this toolkit has, but there are plenty of other great tools there. Good luck!

        Comment

        • rubence
          Banned
          • Jul 2012
          • 1

          #5
          Thanks great info , good dude !

          Comment

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