adding extra factors to topGO object

[MariannePearson]

Hello,

I have created a topGO object using a list of DMRs from BS-seq analysis and wondered if anyone knew of a good way to add whether it is a hypo or hyper methylated region. Can you just add this as a factor? Or would it just be easier to split the DMRs into hypo and hyper groups and perform the analysis separately? I know there is a method to add p-values as a factor so this should be simple in theory but I'm not sure the software lends itself to this analysis.

Any help is appreciated.

Thanks,
Marianne