Hi,I major in Molecular Bio,and what i am doing now need the SOLiD platform.
But I'm totally a green hand in Bioinfo stuff~ Today I got one problem, Maybe someone familiar with the Bioscope (Life Tech) can help me out ?
The diBayes tool in Bioscope pipeline is used to find SNPs.In the Life Tech's Bioscope Guide, about the Reference genome,it's said so:"Note: When you run the SNPs tool, you must use a different reference than the one used for mapping" sadly I only have one Ref version and don't know the reason for a different one~ It's getting more confusing after I read the diBayes Manual--Nothing said about Ref, No rule~
anybody know what's going on?
THANK U VERY MUCH!!
But I'm totally a green hand in Bioinfo stuff~ Today I got one problem, Maybe someone familiar with the Bioscope (Life Tech) can help me out ?
The diBayes tool in Bioscope pipeline is used to find SNPs.In the Life Tech's Bioscope Guide, about the Reference genome,it's said so:"Note: When you run the SNPs tool, you must use a different reference than the one used for mapping" sadly I only have one Ref version and don't know the reason for a different one~ It's getting more confusing after I read the diBayes Manual--Nothing said about Ref, No rule~
anybody know what's going on?
THANK U VERY MUCH!!
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