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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,619 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
684,186 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by YKay, 06-07-2013, 05:34 AM
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2 responses
1,917 views
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by YKay
06-09-2013, 11:51 PM
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Started by Rainbird, 06-09-2013, 06:20 AM
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5 responses
3,210 views
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by Simon Anders
06-09-2013, 10:21 PM
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Started by pari_89, 06-09-2013, 12:51 PM
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1 response
1,388 views
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by GenoMax
06-09-2013, 03:24 PM
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Started by impeachme2, 06-09-2013, 08:34 AM
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0 responses
1,261 views
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by impeachme2
06-09-2013, 08:34 AM
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Started by Morr, 06-09-2013, 07:22 AM
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0 responses
1,763 views
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by Morr
06-09-2013, 07:22 AM
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Started by jeromer, 05-16-2013, 07:00 AM
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2 responses
2,828 views
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by jeromer
06-08-2013, 07:26 PM
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Started by asimons, 02-15-2012, 01:18 PM
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3 responses
3,761 views
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by 12jrowley2
06-08-2013, 05:00 PM
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Started by crazyhottommy, 06-07-2013, 07:35 AM
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3 responses
2,045 views
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Started by SquirrelSeq, 06-07-2013, 06:48 AM
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3 responses
3,733 views
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by mbblack
06-07-2013, 09:54 AM
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Started by nr23, 06-07-2013, 02:29 AM
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3 responses
6,906 views
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Last Post
by sdriscoll
06-07-2013, 09:01 AM
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by SEQadmin2
Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...-
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CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...-
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by SEQadmin2
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...-
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07-20-2026, 11:48 AM -
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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07-09-2026, 11:10 AM -
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Started by SEQadmin2, Today, 02:55 AM
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6 views
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by SEQadmin2
Today, 02:55 AM
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Started by SEQadmin2, 07-24-2026, 12:17 PM
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11 views
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by SEQadmin2
07-24-2026, 12:17 PM
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Started by SEQadmin2, 07-23-2026, 11:41 AM
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by SEQadmin2
07-23-2026, 11:41 AM
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