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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,369 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
683,287 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by Itay.zemach, 05-16-2013, 02:06 AM
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7 responses
3,612 views
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by Itay.zemach
05-30-2013, 02:01 AM
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Started by ddunbar, 05-27-2013, 02:22 AM
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2 responses
1,838 views
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by ddunbar
05-30-2013, 01:45 AM
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Started by Tobikenobi, 05-30-2013, 12:12 AM
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0 responses
1,919 views
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by Tobikenobi
05-30-2013, 12:12 AM
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Started by vidhya, 05-29-2013, 10:38 PM
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1,214 views
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by vidhya
05-29-2013, 10:38 PM
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Started by FLYINGDOLPHIN, 05-29-2013, 06:58 PM
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1 response
1,158 views
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by sdriscoll
05-29-2013, 09:09 PM
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Started by qqsmallfrog, 12-06-2010, 12:37 PM
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13 responses
6,694 views
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by iaia
05-29-2013, 07:50 PM
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Started by juannajuann, 05-28-2013, 10:08 PM
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5 responses
1,986 views
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by kmcarr
05-29-2013, 06:41 PM
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Started by Fernas, 05-29-2013, 11:13 AM
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4 responses
1,874 views
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by chadn737
05-29-2013, 06:05 PM
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Started by mthornton, 05-29-2013, 03:09 PM
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0 responses
1,687 views
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by mthornton
05-29-2013, 03:09 PM
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Started by atruglio, 05-29-2013, 02:59 PM
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0 responses
1,279 views
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by atruglio
05-29-2013, 02:59 PM
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Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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Cancer survival rates have significantly increased in the last few decades in the United States, reaching a combined 70% 5-year survival rate by 2021. Behind this number, there are years of research to find new therapies, drug targets, and early detection methods. But there is one core challenge that keeps slowing down these advances, and it’s about drug resistance.
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07-08-2026, 05:17 AM -
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by GATTACATLove this - good data definitely starts from good input, and poor input can only give relatively poor data. I particularly like the mention of Nanodrop/absorbance based methods for quantification. It's such a toss up if you'll get an accurate reading or what amounts to a randomly generated number, and a lot of library/sequencing related issues can be traced back to poor quant.
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07-01-2026, 11:43 AM -
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Started by SEQadmin2, Yesterday, 10:04 AM
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by SEQadmin2
Yesterday, 10:04 AM
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Started by SEQadmin2, 07-08-2026, 10:08 AM
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by SEQadmin2
07-08-2026, 10:08 AM
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Started by SEQadmin2, 07-07-2026, 11:05 AM
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by SEQadmin2
07-07-2026, 11:05 AM
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