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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,626 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
684,229 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by carolW, 05-24-2013, 12:30 PM
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1 response
5,625 views
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by carolW
05-27-2013, 12:42 AM
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Started by vivienne_lovely, 05-26-2013, 06:49 PM
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1 response
2,590 views
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by swbarnes2
05-26-2013, 10:58 PM
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Started by pengchy, 05-23-2013, 11:14 PM
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1 response
1,155 views
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by pengchy
05-26-2013, 04:14 PM
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Started by ai_seq, 05-26-2013, 03:30 PM
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0 responses
1,231 views
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by ai_seq
05-26-2013, 03:30 PM
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Started by dingkai0564, 08-31-2011, 09:27 PM
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6 responses
4,013 views
0 reactions
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by pari_89
05-26-2013, 01:12 PM
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Started by xinxinding, 05-25-2013, 03:00 PM
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0 responses
1,662 views
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by xinxinding
05-25-2013, 03:00 PM
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Started by Fad2012, 05-23-2013, 02:51 AM
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2 responses
1,247 views
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by Fad2012
05-25-2013, 04:02 AM
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Started by kdarbs, 05-24-2013, 06:17 PM
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0 responses
1,102 views
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by kdarbs
05-24-2013, 06:17 PM
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Started by fahmida, 05-21-2013, 05:14 PM
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10 responses
3,396 views
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by Wallysb01
05-24-2013, 03:24 PM
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Started by nncy1105, 05-24-2013, 11:46 AM
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4 responses
2,384 views
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Last Post
by nncy1105
05-24-2013, 01:44 PM
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by SEQadmin2
Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...-
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CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...-
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by SEQadmin2
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...-
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07-20-2026, 11:48 AM -
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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07-09-2026, 11:10 AM -
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Started by SEQadmin2, Yesterday, 02:55 AM
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9 views
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by SEQadmin2
Yesterday, 02:55 AM
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Started by SEQadmin2, 07-24-2026, 12:17 PM
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12 views
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by SEQadmin2
07-24-2026, 12:17 PM
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Started by SEQadmin2, 07-23-2026, 11:41 AM
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by SEQadmin2
07-23-2026, 11:41 AM
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