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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,550 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
683,928 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by oxydeepu, 05-01-2012, 10:08 PM
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3 responses
2,420 views
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by soban
01-18-2013, 01:42 AM
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Started by Fred13, 12-09-2009, 07:24 AM
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5 responses
5,639 views
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by Fred13
01-18-2013, 01:39 AM
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Started by bharat_iyengar, 01-18-2013, 01:38 AM
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0 responses
2,102 views
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tophat (or tophat-fusion) v2.0.6 error on: Joining segment hits (long_spanning_reads)
by AndrewUzilov
Started by AndrewUzilov, 12-07-2012, 08:26 AM
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6 responses
4,483 views
0 reactions
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by RocheKermit
01-18-2013, 12:25 AM
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Started by papori, 12-04-2012, 06:19 AM
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1 response
1,674 views
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by pengchy
01-17-2013, 10:04 PM
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Started by ajthomas, 01-16-2013, 12:01 PM
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7 responses
1,701 views
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by ajthomas
01-17-2013, 04:25 PM
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Started by NBlackburn, 01-14-2013, 04:53 PM
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2 responses
2,758 views
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by NBlackburn
01-17-2013, 04:12 PM
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Started by dray, 07-13-2012, 05:32 AM
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4 responses
1,673 views
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by crusoe
01-17-2013, 02:43 PM
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Started by yjx1217, 11-18-2011, 03:06 PM
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2 responses
3,525 views
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by yjx1217
01-17-2013, 02:11 PM
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Started by letusgo, 05-04-2012, 07:08 AM
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6 responses
6,321 views
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Last Post
by jb2
01-17-2013, 12:07 PM
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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Cancer survival rates have significantly increased in the last few decades in the United States, reaching a combined 70% 5-year survival rate by 2021. Behind this number, there are years of research to find new therapies, drug targets, and early detection methods. But there is one core challenge that keeps slowing down these advances, and it’s about drug resistance.
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07-08-2026, 05:17 AM -
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by GATTACATLove this - good data definitely starts from good input, and poor input can only give relatively poor data. I particularly like the mention of Nanodrop/absorbance based methods for quantification. It's such a toss up if you'll get an accurate reading or what amounts to a randomly generated number, and a lot of library/sequencing related issues can be traced back to poor quant.
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07-01-2026, 11:43 AM -
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Started by SEQadmin2, 07-13-2026, 10:26 AM
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28 views
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by SEQadmin2
07-13-2026, 10:26 AM
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Started by SEQadmin2, 07-09-2026, 10:04 AM
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by SEQadmin2
07-09-2026, 10:04 AM
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Started by SEQadmin2, 07-08-2026, 10:08 AM
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07-08-2026, 10:08 AM
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