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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,507 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
683,796 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by drdna, 11-22-2012, 06:28 AM
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1 response
4,222 views
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by dpryan
11-22-2012, 10:41 AM
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Started by bob-loblaw, 11-21-2012, 09:00 AM
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1 response
1,261 views
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by lollysticky
11-22-2012, 06:37 AM
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Started by cmczy, 11-21-2012, 11:59 PM
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0 responses
1,149 views
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by cmczy
11-21-2012, 11:59 PM
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Started by Daniel Fernandez, 11-19-2011, 11:00 PM
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30 responses
17,386 views
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by Raul Maia
11-21-2012, 10:18 PM
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Started by Wallysb01, 02-18-2011, 04:31 PM
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1 response
3,187 views
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by sciencewu
11-21-2012, 10:18 PM
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Started by mortonm33, 07-18-2012, 08:30 AM
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4 responses
4,516 views
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by rnaNGS
11-21-2012, 09:28 PM
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Started by czc, 11-20-2012, 11:18 PM
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4 responses
6,596 views
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by czc
11-21-2012, 05:06 PM
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Started by abh, 11-21-2012, 10:06 AM
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1 response
11,353 views
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by dpryan
11-21-2012, 10:59 AM
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Started by angieant, 11-21-2012, 08:58 AM
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0 responses
1,489 views
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by angieant
11-21-2012, 08:58 AM
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Started by erichpeterson, 11-21-2012, 06:51 AM
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2 responses
2,442 views
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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Cancer survival rates have significantly increased in the last few decades in the United States, reaching a combined 70% 5-year survival rate by 2021. Behind this number, there are years of research to find new therapies, drug targets, and early detection methods. But there is one core challenge that keeps slowing down these advances, and it’s about drug resistance.
There is no single reason why many patients don’t respond to treatment as expected. Cancer is...-
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07-08-2026, 05:17 AM -
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by GATTACATLove this - good data definitely starts from good input, and poor input can only give relatively poor data. I particularly like the mention of Nanodrop/absorbance based methods for quantification. It's such a toss up if you'll get an accurate reading or what amounts to a randomly generated number, and a lot of library/sequencing related issues can be traced back to poor quant.
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07-01-2026, 11:43 AM -
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Started by SEQadmin2, 07-13-2026, 10:26 AM
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by SEQadmin2
07-13-2026, 10:26 AM
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Started by SEQadmin2, 07-09-2026, 10:04 AM
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by SEQadmin2
07-09-2026, 10:04 AM
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Started by SEQadmin2, 07-08-2026, 10:08 AM
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by SEQadmin2
07-08-2026, 10:08 AM
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