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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
105,471 views
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by Guest
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
673,290 views
1 like
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Last Post
by ECO
12-25-2009, 06:45 PM
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Started by Giorgio C, 11-29-2011, 07:19 AM
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8 responses
11,024 views
0 likes
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Last Post
by mslider
08-23-2012, 02:29 AM
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Started by kovaliuk, 08-23-2012, 02:28 AM
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0 responses
1,619 views
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by kovaliuk
08-23-2012, 02:28 AM
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Started by kovaliuk, 08-23-2012, 02:25 AM
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0 responses
1,169 views
0 likes
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Last Post
by kovaliuk
08-23-2012, 02:25 AM
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Started by ssully, 08-10-2012, 02:13 PM
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5 responses
9,720 views
0 likes
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Last Post
by Torst
08-22-2012, 09:42 PM
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Started by david.tamborero, 08-08-2011, 07:17 AM
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10 responses
4,478 views
0 likes
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Last Post
by cllorens
08-22-2012, 04:48 PM
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Started by kareldegendt, 03-15-2012, 04:02 PM
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2 responses
3,651 views
0 likes
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Last Post
by mparida
08-22-2012, 03:45 PM
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Started by vpimmett, 08-22-2012, 10:21 AM
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1 response
1,504 views
0 likes
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Last Post 08-22-2012, 11:10 AM | ||
Started by jaaker, 08-22-2012, 09:09 AM
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0 responses
1,983 views
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Last Post
by jaaker
08-22-2012, 09:09 AM
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Started by dkrtndhkd, 08-19-2012, 11:19 PM
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10 responses
3,276 views
0 likes
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Last Post
by swbarnes2
08-22-2012, 08:51 AM
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Started by scibetta, 08-22-2012, 02:43 AM
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1 response
1,132 views
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Last Post
by swbarnes2
08-22-2012, 08:44 AM
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The field of epigenetics has traditionally concentrated more on DNA and how changes like methylation and phosphorylation of histones impact gene expression and regulation. However, our increased understanding of RNA modifications and their importance in cellular processes has led to a rise in epitranscriptomics research. “Epitranscriptomics brings together the concepts of epigenetics and gene expression,” explained Adrien Leger, PhD, Principal Research Scientist...-
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Proteins are often described as the workhorses of the cell, and identifying their sequences is key to understanding their role in biological processes and disease. Currently, the most common technique used to determine protein sequences is mass spectrometry. While still a valuable tool, mass spectrometry faces several limitations and requires a highly experienced scientist familiar with the equipment to operate it. Additionally, other proteomic methods, like affinity assays, are constrained...-
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Despite advancements in sequencing platforms and related sample preparation technologies, certain sample types continue to present significant challenges that can compromise sequencing results. Pedro Echave, Senior Manager of the Global Business Segment at Revvity, explained that the success of a sequencing experiment ultimately depends on the amount and integrity of the nucleic acid template (RNA or DNA) obtained from a sample. “The better the quality of the nucleic acid isolated...-
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