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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,673 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
684,612 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by godzilla07, 08-08-2012, 01:53 PM
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2 responses
1,868 views
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by godzilla07
08-08-2012, 08:22 PM
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Started by aquleaf, 08-08-2012, 08:30 AM
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1 response
1,459 views
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by pbluescript
08-08-2012, 09:41 AM
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Started by mdk308, 08-07-2012, 01:44 PM
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4 responses
1,944 views
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by mdk308
08-08-2012, 07:59 AM
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Started by nposnien, 08-08-2012, 12:07 AM
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4 responses
5,027 views
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by nposnien
08-08-2012, 07:41 AM
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Started by rathankar, 08-08-2012, 04:27 AM
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0 responses
1,481 views
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by rathankar
08-08-2012, 04:27 AM
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Started by yuhao, 08-07-2012, 12:46 AM
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3 responses
1,670 views
0 reactions
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by gprakhar
08-08-2012, 03:24 AM
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Started by ashkot, 08-06-2012, 10:53 AM
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3 responses
1,637 views
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by Bukowski
08-07-2012, 11:53 PM
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Started by me91, 08-07-2012, 01:06 AM
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2 responses
1,329 views
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by me91
08-07-2012, 09:56 PM
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Started by dinkyshmily, 08-06-2012, 11:12 PM
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2 responses
6,562 views
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by dinkyshmily
08-07-2012, 04:59 PM
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Started by lj907, 08-07-2012, 03:18 PM
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0 responses
1,554 views
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by lj907
08-07-2012, 03:18 PM
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by SEQadmin2
Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...-
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07-31-2026, 07:00 AM -
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by SEQadmin2
CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...-
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07-31-2026, 11:01 AM -
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by SEQadmin2
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...-
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07-20-2026, 11:48 AM -
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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Channel: Articles
07-09-2026, 11:10 AM -
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Started by SEQadmin2, Yesterday, 07:41 AM
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12 views
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by SEQadmin2
Yesterday, 07:41 AM
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Started by SEQadmin2, 08-03-2026, 10:13 AM
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0 responses
25 views
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by SEQadmin2
08-03-2026, 10:13 AM
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Started by SEQadmin2, 07-31-2026, 02:55 AM
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0 responses
38 views
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by SEQadmin2
07-31-2026, 02:55 AM
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