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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,650 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
684,396 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by nkaushik, 05-31-2012, 03:35 AM
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2 responses
2,143 views
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by NextGenSeq
05-31-2012, 01:23 PM
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Started by NestorNotabilis, 05-30-2012, 12:33 AM
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3 responses
2,217 views
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by bioinfosm
05-31-2012, 11:25 AM
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Started by lg36, 05-31-2012, 10:36 AM
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2 responses
1,919 views
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by lg36
05-31-2012, 11:24 AM
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Started by golharam, 05-31-2012, 10:42 AM
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0 responses
2,672 views
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by golharam
05-31-2012, 10:42 AM
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Started by elfuser, 05-31-2012, 08:40 AM
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2 responses
2,667 views
0 reactions
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by elfuser
05-31-2012, 10:40 AM
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Started by pag, 05-18-2012, 08:52 AM
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12 responses
3,375 views
0 reactions
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by pag
05-31-2012, 10:26 AM
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Started by gmer, 05-31-2012, 06:05 AM
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1 response
2,242 views
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by GenoMax
05-31-2012, 08:46 AM
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Started by desmo, 05-30-2012, 03:04 AM
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4 responses
2,716 views
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by desmo
05-31-2012, 07:28 AM
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Started by fozturk, 05-30-2012, 10:25 AM
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2 responses
3,882 views
0 reactions
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by Bukowski
05-31-2012, 05:04 AM
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Started by NicoBxl, 12-13-2010, 12:36 AM
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6 responses
9,690 views
0 reactions
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Last Post
by dan
05-30-2012, 11:25 PM
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by SEQadmin2
Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...-
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07-31-2026, 07:00 AM -
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by SEQadmin2
CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...-
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07-31-2026, 11:01 AM -
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by SEQadmin2
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...-
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07-20-2026, 11:48 AM -
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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07-09-2026, 11:10 AM -
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Started by SEQadmin2, Today, 10:13 AM
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0 responses
7 views
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by SEQadmin2
Today, 10:13 AM
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Started by SEQadmin2, 07-31-2026, 02:55 AM
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0 responses
20 views
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by SEQadmin2
07-31-2026, 02:55 AM
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Started by SEQadmin2, 07-24-2026, 12:17 PM
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0 responses
17 views
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by SEQadmin2
07-24-2026, 12:17 PM
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