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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,723 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
685,602 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by Alex Clop, 08-12-2010, 04:31 AM
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1 response
3,304 views
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by adamdeluca
08-12-2010, 05:13 AM
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Started by ljxue, 08-03-2009, 06:16 PM
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2 responses
2,707 views
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by sclindsay
08-11-2010, 09:16 PM
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Started by lazyworm, 08-11-2010, 09:44 AM
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1 response
4,232 views
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by Lee Sam
08-11-2010, 10:03 AM
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Started by syslm01, 08-11-2010, 03:48 AM
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1,686 views
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by syslm01
08-11-2010, 03:48 AM
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Started by repinementer, 08-10-2010, 06:55 PM
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1 response
2,391 views
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Started by repinementer, 08-10-2010, 11:05 PM
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0 responses
2,369 views
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by repinementer
08-10-2010, 11:05 PM
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Started by Yushan Hsiao, 08-10-2010, 09:54 PM
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0 responses
1,945 views
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by Yushan Hsiao
08-10-2010, 09:54 PM
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Started by jkbonfield, 08-10-2010, 04:41 AM
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6 responses
6,749 views
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by jkbonfield
08-10-2010, 03:12 PM
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Started by litd, 07-14-2010, 06:53 AM
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2 responses
2,364 views
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by angelawu
08-10-2010, 02:43 PM
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Started by Ms@New, 08-03-2010, 11:20 AM
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4 responses
1,843 views
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by Ms@New
08-10-2010, 01:02 PM
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by SEQadmin2
Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...-
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07-31-2026, 07:00 AM -
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by SEQadmin2
CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...-
Channel: Articles
07-31-2026, 11:01 AM -
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by SEQadmin2
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...-
Channel: Articles
07-20-2026, 11:48 AM -
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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Channel: Articles
07-09-2026, 11:10 AM -
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Started by SEQadmin2, Today, 10:32 AM
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4 views
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by SEQadmin2
Today, 10:32 AM
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Started by SEQadmin2, 08-20-2026, 11:17 AM
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27 views
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by SEQadmin2
08-20-2026, 11:17 AM
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Started by SEQadmin2, 08-18-2026, 10:05 AM
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30 views
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by SEQadmin2
08-18-2026, 10:05 AM
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