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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,622 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
684,220 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by qnc, 10-17-2011, 04:56 AM
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4 responses
4,934 views
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by qnc
10-17-2011, 10:15 AM
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Started by loba17, 10-14-2011, 12:25 AM
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4 responses
3,880 views
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by loba17
10-17-2011, 07:31 AM
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Started by flobpf, 10-14-2011, 11:04 AM
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2 responses
3,180 views
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by flobpf
10-17-2011, 07:14 AM
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Started by jiyan, 10-16-2011, 07:42 PM
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1 response
2,304 views
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by Emilie
10-17-2011, 07:06 AM
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Started by victoryhe, 10-12-2011, 10:18 AM
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2 responses
8,158 views
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by victoryhe
10-17-2011, 04:53 AM
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Started by Ramprasad, 10-16-2011, 10:18 PM
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0 responses
5,921 views
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by Ramprasad
10-16-2011, 10:18 PM
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Started by efoss, 10-15-2011, 06:24 AM
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4 responses
4,283 views
0 reactions
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by efoss
10-16-2011, 08:11 PM
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Started by jiyan, 10-16-2011, 07:32 PM
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0 responses
3,274 views
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by jiyan
10-16-2011, 07:32 PM
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Started by sclindsay, 08-04-2011, 09:58 PM
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1 response
2,257 views
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by lindymcb
10-16-2011, 01:22 PM
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Started by feng, 06-23-2011, 12:58 PM
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3 responses
2,315 views
0 reactions
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Last Post
by spenthil
10-16-2011, 09:50 AM
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Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...-
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CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...-
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by SEQadmin2
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...-
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07-20-2026, 11:48 AM -
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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07-09-2026, 11:10 AM -
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Started by SEQadmin2, Yesterday, 02:55 AM
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9 views
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by SEQadmin2
Yesterday, 02:55 AM
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Started by SEQadmin2, 07-24-2026, 12:17 PM
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12 views
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by SEQadmin2
07-24-2026, 12:17 PM
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Started by SEQadmin2, 07-23-2026, 11:41 AM
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by SEQadmin2
07-23-2026, 11:41 AM
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