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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,627 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
684,233 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by harshinamdar, 08-24-2011, 04:17 AM
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1 response
1,735 views
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by kmcarr
08-24-2011, 05:16 AM
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Started by davidehs, 08-23-2011, 07:55 AM
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5 responses
2,915 views
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by davidehs
08-24-2011, 04:07 AM
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Started by burt, 08-23-2011, 11:59 PM
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0 responses
3,445 views
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by burt
08-23-2011, 11:59 PM
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Started by byou678, 08-19-2011, 02:48 PM
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18 responses
12,509 views
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by byou678
08-23-2011, 01:53 PM
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Started by camelbbs, 08-23-2011, 12:57 PM
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0 responses
1,691 views
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by camelbbs
08-23-2011, 12:57 PM
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Started by chenyao, 08-18-2011, 10:24 PM
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9 responses
4,201 views
0 reactions
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by westerman
08-23-2011, 09:50 AM
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Started by shuang, 08-23-2011, 06:03 AM
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0 responses
1,529 views
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by shuang
08-23-2011, 06:03 AM
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Started by zhidong, 08-18-2011, 10:30 PM
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5 responses
2,596 views
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Last Post
by macrowave
08-23-2011, 05:10 AM
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Started by chenyao, 08-23-2011, 01:18 AM
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3 responses
2,965 views
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by chenyao
08-23-2011, 05:06 AM
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Started by moriah, 08-21-2011, 01:35 AM
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3 responses
2,792 views
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Last Post
by moriah
08-23-2011, 01:46 AM
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by SEQadmin2
Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...-
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CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...-
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by SEQadmin2
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...-
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07-20-2026, 11:48 AM -
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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07-09-2026, 11:10 AM -
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Started by SEQadmin2, Yesterday, 02:55 AM
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9 views
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by SEQadmin2
Yesterday, 02:55 AM
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Started by SEQadmin2, 07-24-2026, 12:17 PM
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12 views
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by SEQadmin2
07-24-2026, 12:17 PM
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Started by SEQadmin2, 07-23-2026, 11:41 AM
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12 views
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by SEQadmin2
07-23-2026, 11:41 AM
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