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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
683,191 views
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by ECO
12-25-2009, 06:45 PM
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shinyheatmap: Ultra fast low memory heatmap web interface for big data genomics
by Bohdan_Khomtchouk
Started by Bohdan_Khomtchouk, 05-14-2017, 02:43 PM
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2,922 views
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shinyheatmap: Ultra fast low memory heatmap web interface for big data genomics
by Bohdan_Khomtchouk
Started by Bohdan_Khomtchouk, 05-14-2017, 12:08 PM
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13 views
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Started by naono, 04-23-2017, 08:22 PM
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3 responses
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by naono
05-12-2017, 11:49 PM
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Started by confurious, 04-18-2017, 02:13 PM
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19 responses
6,231 views
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Started by saldi, 05-12-2017, 10:52 AM
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5 responses
1,645 views
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Started by ohakoh, 05-12-2017, 11:28 AM
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by ohakoh
05-12-2017, 11:28 AM
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Started by lre1234, 05-12-2017, 08:40 AM
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1,050 views
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by lre1234
05-12-2017, 08:40 AM
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Started by RobbenStijn, 05-09-2017, 05:15 AM
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2 responses
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by RobbenStijn
05-11-2017, 12:29 AM
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Started by jorvis, 05-10-2017, 08:03 PM
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3 responses
3,687 views
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by gringer
05-11-2017, 12:11 AM
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Started by pdblood, 05-03-2017, 06:55 AM
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1 response
2,161 views
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by Melissa
05-09-2017, 05:05 AM
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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Cancer survival rates have significantly increased in the last few decades in the United States, reaching a combined 70% 5-year survival rate by 2021. Behind this number, there are years of research to find new therapies, drug targets, and early detection methods. But there is one core challenge that keeps slowing down these advances, and it’s about drug resistance.
There is no single reason why many patients don’t respond to treatment as expected. Cancer is...-
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Yesterday, 05:17 AM -
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by GATTACATLove this - good data definitely starts from good input, and poor input can only give relatively poor data. I particularly like the mention of Nanodrop/absorbance based methods for quantification. It's such a toss up if you'll get an accurate reading or what amounts to a randomly generated number, and a lot of library/sequencing related issues can be traced back to poor quant.
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07-01-2026, 11:43 AM -
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Started by SEQadmin2, Today, 10:04 AM
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Today, 10:04 AM
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Started by SEQadmin2, Yesterday, 10:08 AM
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Yesterday, 10:08 AM
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Started by SEQadmin2, 07-07-2026, 11:05 AM
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07-07-2026, 11:05 AM
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