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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,340 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
683,117 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by junkfish, 02-17-2010, 03:03 PM
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2 responses
2,899 views
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by drio
02-18-2010, 08:36 AM
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Started by saima, 02-18-2010, 01:30 AM
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2 responses
1,801 views
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by saima
02-18-2010, 05:32 AM
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Started by spindrift, 02-17-2010, 02:57 AM
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4 responses
2,451 views
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by spindrift
02-17-2010, 11:20 AM
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Started by bioenvisage, 02-16-2010, 08:10 AM
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1 response
1,749 views
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by Zigster
02-17-2010, 09:16 AM
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Started by lcollado, 02-16-2010, 05:51 PM
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1 response
1,710 views
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by lcollado
02-16-2010, 06:04 PM
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Started by crinfante, 02-16-2010, 01:07 PM
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3 responses
3,144 views
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by shurjo
02-16-2010, 03:14 PM
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Started by ECHo, 02-16-2010, 08:29 AM
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0 responses
1,964 views
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by ECHo
02-16-2010, 08:29 AM
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Started by zslee, 02-08-2010, 06:15 AM
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5 responses
2,560 views
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by steven
02-16-2010, 03:52 AM
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Started by DCarone, 03-11-2009, 11:24 AM
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4 responses
3,350 views
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by begsch
02-16-2010, 02:07 AM
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Started by sunyu1357, 02-11-2010, 12:06 PM
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2 responses
3,051 views
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Cancer survival rates have significantly increased in the last few decades in the United States, reaching a combined 70% 5-year survival rate by 2021. Behind this number, there are years of research to find new therapies, drug targets, and early detection methods. But there is one core challenge that keeps slowing down these advances, and it’s about drug resistance.
There is no single reason why many patients don’t respond to treatment as expected. Cancer is...-
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by GATTACATLove this - good data definitely starts from good input, and poor input can only give relatively poor data. I particularly like the mention of Nanodrop/absorbance based methods for quantification. It's such a toss up if you'll get an accurate reading or what amounts to a randomly generated number, and a lot of library/sequencing related issues can be traced back to poor quant.
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07-01-2026, 11:43 AM -
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by SEQadmin2
I’m not a sequencing expert. I’m a purification scientist who uses NGS to evaluate workflows my group develops. With this perspective, we think about the sample first and the NGS workflow second. The sequencer is an exceptionally honest reporter, but it can only report on what you give it, so whether you get clean, interpretable data from an NGS workflow is largely determined before you begin.
Here are nine questions we think about, in roughly the order they matter, before...-
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Yesterday, 10:08 AM
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Started by SEQadmin2, 07-07-2026, 11:05 AM
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07-07-2026, 11:05 AM
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Started by SEQadmin2, 07-02-2026, 11:08 AM
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07-02-2026, 11:08 AM
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