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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,520 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
683,817 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by analyst, 11-25-2011, 03:09 PM
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14 responses
15,265 views
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by pmiguel
02-15-2017, 07:25 AM
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Started by lre1234, 02-13-2017, 01:04 PM
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2 responses
1,524 views
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by lre1234
02-15-2017, 05:49 AM
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Started by finswimmer, 01-25-2017, 05:37 AM
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4 responses
2,173 views
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by finswimmer
02-14-2017, 09:02 PM
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Started by cmonat, 02-10-2017, 07:27 AM
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1 response
3,377 views
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by finswimmer
02-14-2017, 08:57 PM
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Started by mrfox, 02-13-2017, 09:16 AM
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4 responses
1,786 views
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by swbarnes2
02-14-2017, 01:37 PM
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Started by ClemBuntu, 10-18-2015, 03:57 AM
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4 responses
5,459 views
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by minie
02-14-2017, 02:04 AM
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Started by crvalenz, 11-22-2016, 08:25 PM
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5 responses
4,278 views
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by tony.travis
02-13-2017, 04:14 AM
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Started by mparida, 02-06-2017, 05:28 PM
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1 response
3,156 views
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by mparida
02-11-2017, 01:05 PM
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Started by Bourney, 02-11-2017, 02:20 AM
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1 response
2,956 views
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Started by foolishbrat, 02-10-2017, 05:13 PM
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4 responses
5,820 views
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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07-09-2026, 11:10 AM -
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by SEQadmin2
Cancer survival rates have significantly increased in the last few decades in the United States, reaching a combined 70% 5-year survival rate by 2021. Behind this number, there are years of research to find new therapies, drug targets, and early detection methods. But there is one core challenge that keeps slowing down these advances, and it’s about drug resistance.
There is no single reason why many patients don’t respond to treatment as expected. Cancer is...-
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07-08-2026, 05:17 AM -
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by GATTACATLove this - good data definitely starts from good input, and poor input can only give relatively poor data. I particularly like the mention of Nanodrop/absorbance based methods for quantification. It's such a toss up if you'll get an accurate reading or what amounts to a randomly generated number, and a lot of library/sequencing related issues can be traced back to poor quant.
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07-01-2026, 11:43 AM -
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Started by SEQadmin2, 07-13-2026, 10:26 AM
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24 views
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by SEQadmin2
07-13-2026, 10:26 AM
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Started by SEQadmin2, 07-09-2026, 10:04 AM
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by SEQadmin2
07-09-2026, 10:04 AM
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Started by SEQadmin2, 07-08-2026, 10:08 AM
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by SEQadmin2
07-08-2026, 10:08 AM
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