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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
683,318 views
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by ECO
12-25-2009, 06:45 PM
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Started by michalkovac, 11-25-2010, 03:15 AM
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14 responses
13,816 views
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by Idon_Sokolov
01-16-2017, 10:37 AM
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Started by dcromie, 01-16-2017, 05:55 AM
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by dcromie
01-16-2017, 05:55 AM
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Started by capricy, 01-14-2017, 04:48 AM
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2 responses
3,790 views
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by capricy
01-16-2017, 02:18 AM
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Started by dsher, 12-19-2016, 11:38 PM
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4 responses
4,178 views
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by dsher
01-14-2017, 09:49 AM
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Started by divya, 01-12-2017, 05:01 AM
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3 responses
2,356 views
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by divya
01-12-2017, 08:50 PM
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Started by rama, 01-14-2013, 01:30 PM
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7 responses
4,374 views
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by tedtoal
01-12-2017, 04:58 PM
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Started by kingcohn1, 01-11-2017, 11:36 AM
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4 responses
2,336 views
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Started by lre1234, 01-12-2017, 12:52 PM
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1,648 views
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by lre1234
01-12-2017, 12:52 PM
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Started by JamesSeward, 01-12-2017, 12:11 PM
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1,367 views
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by JamesSeward
01-12-2017, 12:11 PM
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Started by Joseph White, 01-12-2017, 11:07 AM
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2,055 views
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by Joseph White
01-12-2017, 11:07 AM
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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Cancer survival rates have significantly increased in the last few decades in the United States, reaching a combined 70% 5-year survival rate by 2021. Behind this number, there are years of research to find new therapies, drug targets, and early detection methods. But there is one core challenge that keeps slowing down these advances, and it’s about drug resistance.
There is no single reason why many patients don’t respond to treatment as expected. Cancer is...-
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07-08-2026, 05:17 AM -
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by GATTACATLove this - good data definitely starts from good input, and poor input can only give relatively poor data. I particularly like the mention of Nanodrop/absorbance based methods for quantification. It's such a toss up if you'll get an accurate reading or what amounts to a randomly generated number, and a lot of library/sequencing related issues can be traced back to poor quant.
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07-01-2026, 11:43 AM -
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Started by SEQadmin2, Yesterday, 10:04 AM
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by SEQadmin2
Yesterday, 10:04 AM
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Started by SEQadmin2, 07-08-2026, 10:08 AM
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by SEQadmin2
07-08-2026, 10:08 AM
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Started by SEQadmin2, 07-07-2026, 11:05 AM
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by SEQadmin2
07-07-2026, 11:05 AM
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