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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,645 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
684,377 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by anjali@iiser, 06-22-2021, 10:24 PM
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0 responses
2,060 views
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by anjali@iiser
06-22-2021, 10:24 PM
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Started by efoss, 10-24-2011, 10:08 AM
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3 responses
17,036 views
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by Proguide
06-22-2021, 05:12 PM
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Started by GSviral, 06-22-2021, 04:53 AM
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0 responses
1,844 views
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by GSviral
06-22-2021, 04:53 AM
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Started by karlae05, 06-16-2021, 08:07 AM
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2,473 views
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by karlae05
06-16-2021, 08:07 AM
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Started by satellitesy, 06-14-2021, 08:12 PM
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0 responses
1,953 views
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by satellitesy
06-14-2021, 08:12 PM
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Started by _anli, 06-07-2021, 11:06 PM
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0 responses
2,415 views
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by _anli
06-07-2021, 11:06 PM
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Started by Hedi86, 06-07-2021, 12:19 AM
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0 responses
2,527 views
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by Hedi86
06-07-2021, 12:19 AM
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Started by khoulahan, 01-27-2014, 06:15 AM
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8 responses
133,792 views
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by sushilsonee
06-04-2021, 11:18 PM
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Started by Manuelita, 06-03-2021, 05:42 AM
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0 responses
162 views
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by Manuelita
06-03-2021, 05:42 AM
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Started by Manuelita, 06-03-2021, 04:54 AM
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0 responses
2,165 views
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by Manuelita
06-03-2021, 04:54 AM
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by SEQadmin2
Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...-
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07-31-2026, 07:00 AM -
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by SEQadmin2
CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...-
Channel: Articles
07-31-2026, 11:01 AM -
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by SEQadmin2
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...-
Channel: Articles
07-20-2026, 11:48 AM -
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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Channel: Articles
07-09-2026, 11:10 AM -
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Started by SEQadmin2, 07-31-2026, 02:55 AM
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20 views
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by SEQadmin2
07-31-2026, 02:55 AM
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Started by SEQadmin2, 07-24-2026, 12:17 PM
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0 responses
16 views
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by SEQadmin2
07-24-2026, 12:17 PM
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Started by SEQadmin2, 07-23-2026, 11:41 AM
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16 views
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by SEQadmin2
07-23-2026, 11:41 AM
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