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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,729 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
685,705 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by aquinom85, 04-06-2012, 07:00 AM
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3 responses
2,413 views
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by tlee233
07-13-2015, 07:25 AM
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Started by skbrimer, 07-13-2015, 06:42 AM
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0 responses
1,092 views
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by skbrimer
07-13-2015, 06:42 AM
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Started by carp, 07-06-2015, 11:32 AM
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9 responses
2,526 views
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by carp
07-13-2015, 06:36 AM
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Started by shadow19c, 07-12-2015, 11:09 PM
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1 response
3,257 views
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by chrisamiller
07-13-2015, 05:03 AM
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Started by Strandlife, 07-13-2015, 12:08 AM
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0 responses
2,661 views
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by Strandlife
07-13-2015, 12:08 AM
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Started by hemgupt1, 07-12-2015, 09:28 PM
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0 responses
1,456 views
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by hemgupt1
07-12-2015, 09:28 PM
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Started by lavik17, 07-12-2015, 05:53 AM
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0 responses
1,652 views
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by lavik17
07-12-2015, 05:53 AM
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Started by francohalpert, 04-18-2014, 07:28 AM
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1 response
2,389 views
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by Karli_40
07-11-2015, 06:48 PM
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Started by NYGen, 07-11-2015, 05:39 PM
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0 responses
2,563 views
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by NYGen
07-11-2015, 05:39 PM
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Started by ALB_1, 04-18-2013, 07:53 AM
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23 responses
36,894 views
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Last Post
by sciseim
07-11-2015, 05:12 PM
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by SEQadmin2
Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...-
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07-31-2026, 07:00 AM -
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by SEQadmin2
CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...-
Channel: Articles
07-31-2026, 11:01 AM -
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by SEQadmin2
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...-
Channel: Articles
07-20-2026, 11:48 AM -
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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Channel: Articles
07-09-2026, 11:10 AM -
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Started by SEQadmin2, 08-24-2026, 10:32 AM
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0 responses
10 views
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by SEQadmin2
08-24-2026, 10:32 AM
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Started by SEQadmin2, 08-20-2026, 11:17 AM
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0 responses
33 views
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by SEQadmin2
08-20-2026, 11:17 AM
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Started by SEQadmin2, 08-18-2026, 10:05 AM
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0 responses
37 views
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by SEQadmin2
08-18-2026, 10:05 AM
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