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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,692 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
685,081 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by traeki, 09-29-2014, 01:09 AM
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8 responses
2,202 views
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by traeki
09-29-2014, 11:59 AM
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Started by papori, 09-28-2014, 01:41 AM
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4 responses
1,783 views
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by papori
09-29-2014, 10:03 AM
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Started by trakhtenberg, 09-29-2014, 09:32 AM
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0 responses
1,904 views
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by trakhtenberg
09-29-2014, 09:32 AM
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Started by bioman1, 09-28-2014, 10:24 PM
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2 responses
2,712 views
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by ssully
09-29-2014, 09:05 AM
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Started by lucio89, 09-26-2014, 06:52 PM
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2 responses
7,832 views
0 reactions
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by maubp
09-29-2014, 08:56 AM
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Started by heso, 09-29-2014, 04:28 AM
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1 response
2,299 views
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by dpryan
09-29-2014, 04:48 AM
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Started by icg, 09-28-2014, 10:26 PM
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2 responses
1,324 views
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by icg
09-29-2014, 04:28 AM
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Started by deuterium, 09-28-2014, 11:20 PM
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0 responses
1,044 views
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by deuterium
09-28-2014, 11:20 PM
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Started by SpreeFu, 02-05-2014, 03:23 AM
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7 responses
4,833 views
0 reactions
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by ysnapus
09-28-2014, 09:14 PM
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Started by lre1234, 09-28-2014, 01:18 PM
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1 response
7,808 views
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Last Post
by dpryan
09-28-2014, 01:27 PM
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by SEQadmin2
Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...-
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07-31-2026, 07:00 AM -
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by SEQadmin2
CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...-
Channel: Articles
07-31-2026, 11:01 AM -
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by SEQadmin2
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...-
Channel: Articles
07-20-2026, 11:48 AM -
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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Channel: Articles
07-09-2026, 11:10 AM -
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Started by SEQadmin2, 08-13-2026, 12:22 PM
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0 responses
20 views
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by SEQadmin2
08-13-2026, 12:22 PM
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Started by SEQadmin2, 08-11-2026, 10:35 AM
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0 responses
16 views
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by SEQadmin2
08-11-2026, 10:35 AM
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Started by SEQadmin2, 08-06-2026, 07:41 AM
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0 responses
32 views
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by SEQadmin2
08-06-2026, 07:41 AM
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