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New Resources for 1000 Genomes
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35 responses
108,000 views
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by laura
12-05-2013, 02:37 AM
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Software packages for next gen sequence analysis
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236 responses
688,160 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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0 responses
1,078 views
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by Nick
09-12-2014, 07:57 AM
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10,467 views
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09-12-2014, 06:39 AM
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2,550 views
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by tonybolger
09-12-2014, 04:08 AM
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by cast457
09-12-2014, 01:05 AM
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8 responses
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09-11-2014, 08:36 PM
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by i19870503
09-11-2014, 06:41 PM
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9,115 views
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by lh3
09-11-2014, 05:19 PM
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3,821 views
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by Gordon Smyth
09-11-2014, 03:47 PM
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1 response
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09-11-2014, 01:14 PM
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09-11-2014, 10:29 AM
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Researchers using sequencing and genomics tools often have to make trade-offs. They can choose between speed or scale, short reads or long-range information, or targeted panels or a view of the whole transcriptome. New technologies that have been released this year are built to address those tough choices.
We asked six companies the same four questions to learn about their latest products. The new technologies bring a lot to the table, including rethinking sequencing... -
The immune system’s power comes from its genetic diversity, allowing myriad threats to be neutralized through first recognizing foreign antigens. That diversity is also what makes the immune system so difficult to study. Recent advances in sequencing technology and computational biology, however, are giving researchers new tools to understand immune responses and immune-related diseases in greater detail.
This convergence of genetics, immunology, and computation...09-01-2026, 05:41 AM -
CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...07-31-2026, 11:01 AM