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Closed, Sticky:
New Resources for 1000 Genomes
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35 responses
107,228 views
0 reactions
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by laura
12-05-2013, 02:37 AM
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Closed, Sticky:
Software packages for next gen sequence analysis
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236 responses
681,681 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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6 responses
2,581 views
0 reactions
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by jpummil
09-08-2014, 10:30 AM
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3 responses
2,467 views
0 reactions
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by kbradnam
09-08-2014, 07:45 AM
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1 response
1,954 views
0 reactions
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by kbradnam
09-08-2014, 07:43 AM
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6 responses
6,666 views
0 reactions
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by Michael Love
09-08-2014, 04:18 AM
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0 responses
1,230 views
0 reactions
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by bioWizz
09-08-2014, 03:17 AM
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1 response
1,575 views
0 reactions
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by dpryan
09-08-2014, 02:06 AM
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7 responses
3,585 views
0 reactions
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by smowton
09-08-2014, 01:38 AM
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3 responses
1,441 views
0 reactions
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by bastianwur
09-07-2014, 11:40 PM
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4 responses
7,001 views
0 reactions
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by ksw9
09-07-2014, 02:52 PM
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8 responses
12,249 views
0 reactions
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by louis_ly
09-07-2014, 06:40 AM
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No topics found.
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Childhood cancers, effectively fatal 60 years ago, are now curable for up to 85% of children with access to contemporary treatments and...05-08-2026, 01:42 AM
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I’m not a sequencing expert. I’m a purification scientist who uses NGS to evaluate workflows my group develops. With this perspective, we think about the sample first and the NGS workflow second. The sequencer is an exceptionally honest reporter, but it can only report on what you give it, so whether you get clean, interpretable data from an NGS workflow is largely determined before you begin.
Here are nine questions we think about, in roughly the order they matter, before...06-18-2026, 07:11 AM -
Data variability is still an issue in sequencing technologies despite the advances in reproducibility and accuracy of these platforms. But the problem does not originate in the sequencing itself, but in the previous steps, before the sample reaches the sequencer.
The first step is collection, followed by preservation and sample preparation for analysis. Most scientists overlook those steps, but not being careful might just be skewing the experiment’s results.
...06-02-2026, 10:05 AM -
With the launch of new single-cell sequencing platforms in 2026, the field stands at an exciting inflection point. This article surveys the most impactful advances in the field and discusses how they’re reshaping research in cancer, immunology, and beyond.
Introduction
Single-cell sequencing technologies have undergone remarkable advances over the past decade, transitioning from low-throughput experimental approaches to highly scalable platforms capable of...05-22-2026, 06:42 AM