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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,682 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
684,986 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by Joseph White, 05-09-2018, 03:04 AM
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7 responses
6,088 views
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by aimeeclair
12-12-2019, 07:31 AM
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Started by mavershang, 12-11-2019, 12:24 PM
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0 responses
1,689 views
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by mavershang
12-11-2019, 12:24 PM
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Started by an_na, 11-28-2019, 05:01 AM
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1 response
2,062 views
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by Melissa
12-10-2019, 05:50 AM
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Started by AxelM, 12-09-2019, 06:54 AM
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4,884 views
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by AxelM
12-09-2019, 06:54 AM
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Started by Guest, 12-07-2019, 04:56 AM
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0 responses
1,927 views
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by Guest
12-07-2019, 04:56 AM
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Started by mwarrier, 12-05-2019, 01:22 PM
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0 responses
38 views
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by mwarrier
12-05-2019, 01:22 PM
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Started by sdmoore, 12-04-2019, 01:13 PM
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0 responses
132 views
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by sdmoore
12-04-2019, 01:13 PM
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BWA problem
by hche
Started by hche, 12-04-2019, 10:21 AM
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1 response
4,710 views
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by hche
12-04-2019, 10:33 AM
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Started by an_na, 11-28-2019, 04:48 AM
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0 responses
46 views
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by an_na
11-28-2019, 04:48 AM
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Started by pacbio, 11-25-2019, 01:53 PM
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2,065 views
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by pacbio
11-25-2019, 01:53 PM
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by SEQadmin2
Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...-
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07-31-2026, 07:00 AM -
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by SEQadmin2
CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...-
Channel: Articles
07-31-2026, 11:01 AM -
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by SEQadmin2
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...-
Channel: Articles
07-20-2026, 11:48 AM -
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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Channel: Articles
07-09-2026, 11:10 AM -
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Started by SEQadmin2, Today, 12:22 PM
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12 views
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by SEQadmin2
Today, 12:22 PM
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Started by SEQadmin2, 08-11-2026, 10:35 AM
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11 views
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by SEQadmin2
08-11-2026, 10:35 AM
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Started by SEQadmin2, 08-06-2026, 07:41 AM
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30 views
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by SEQadmin2
08-06-2026, 07:41 AM
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