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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,628 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
684,246 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by Genospect, 02-16-2025, 01:21 AM
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0 responses
109 views
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by Genospect
02-16-2025, 01:21 AM
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Started by ag2024, 02-11-2025, 03:21 PM
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1 response
199 views
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by fchatonnet
02-12-2025, 02:16 AM
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Started by M.Askari, 01-29-2025, 07:58 AM
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2 responses
259 views
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by fchatonnet
02-12-2025, 02:03 AM
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Single-Cell RNA-Seq Data Analysis: A Practical Introduction (March 17-19, 2025 in Berlin, Germany)
by ecSeq Bioinformatics
Started by ecSeq Bioinformatics, 02-12-2025, 12:06 AM
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0 responses
53 views
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Started by gvilly, 01-26-2025, 07:38 PM
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170 views
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by gvilly
01-26-2025, 07:38 PM
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Started by shawn.mek, 10-28-2013, 06:28 AM
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10 responses
5,643 views
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by tatianaorli
01-21-2025, 04:50 AM
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Started by ksv6178, 11-25-2024, 07:23 PM
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1 response
239 views
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by ovon
01-08-2025, 12:40 PM
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How can I filter ASVs by similarity during alignment, in prep for placement into a phylogenetic tree
by ovon
Started by ovon, 01-08-2025, 10:45 AM
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0 responses
134 views
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by ovon
01-08-2025, 10:45 AM
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Started by dsturgill, 11-18-2024, 02:05 PM
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69 views
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by dsturgill
11-18-2024, 02:05 PM
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Started by Brian Bushnell, 02-19-2014, 01:33 PM
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725 responses
335,245 views
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by nmhannon
11-14-2024, 01:08 AM
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by SEQadmin2
Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...-
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by SEQadmin2
CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...-
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by SEQadmin2
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...-
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07-20-2026, 11:48 AM -
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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07-09-2026, 11:10 AM -
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Started by SEQadmin2, Yesterday, 02:55 AM
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9 views
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by SEQadmin2
Yesterday, 02:55 AM
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Started by SEQadmin2, 07-24-2026, 12:17 PM
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by SEQadmin2
07-24-2026, 12:17 PM
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Started by SEQadmin2, 07-23-2026, 11:41 AM
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by SEQadmin2
07-23-2026, 11:41 AM
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