Comparing mouse and human differentially expressed genes

[stephenhart]

Hello,

I have run differential expression analyses for mouse and human using RNA-seq data. I now have a list of genes (Ensembl IDs) differentially expressed in the mouse and a list of genes differentially expressed in the human. How can I now see if there is any overlap between the lists? Clearly I cannot use the Ensembl IDs, and many gene symbols differ between mouse and human. Any advice would be appreciated.

Thanks
Stephan

[kmcarr]

Look at this link. It's a little outdated but should give a start.

[marcowanger]

Stephen you might want to know more on the synteny blocks between mouse and human

http://www.evolutionpages.com/Mouse%20genome%20synteny.htm

[MichalO]

Look at this link. It's a little outdated but should give a start.

Yup. Translate the Ensembl IDs from human to mouse orthologs using biomart.org - then you'll have the quite complete table.