Multiple Instances of GS Assembler

[omerfaruk]

Hello,

GS Assembler is currently running incrementally in a machine with 1 TB RAM, still taking months since data is 600 GB.

Can I run multiple separate instances for one file at a time at different machines, like 16 files, 16 machines, and then in a way, unify these results?

Best,

[flxlex]

Not directly out of the box. Do you need all that data (what are you assembling)? If you do, can you do digital normalisation, or partioning (e.g., see the khmer package)

[omerfaruk]

I have like 40 files, 3-4 gbs each. Adding one file at a time, incremental, large genome, het.

[flxlex]

What is the total coverage (total sequenced bp divided by genome size)? Your data should be OK for newbler in one go...