Has anyone had a problem with the RFID reader with the NextSeq 500 sequencer? I believe this is the problem I am having with mine as it doesn't recognize or cannot read the flow cells when either trying to wash or run samples.
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Todd D Prickett
NCI/NIH
Research Fellow
10 Center Dr
Building 10 CRC, rm. 3W-3864
Bethesda, MD 20892 -
We have run into this problem twice before. Illumina recommended power cycling the instrument (close out of all programs, hold power button on the front of instrument until it completely turns off, wait 5 minutes, power back on.). This has worked on both occasions. Good luck! -
This sounds like a good idea, thank you for the suggestion. I will post later if it works!Todd D Prickett
NCI/NIH
Research Fellow
10 Center Dr
Building 10 CRC, rm. 3W-3864
Bethesda, MD 20892Comment
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CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...07-31-2026, 11:01 AM -
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
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Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
...07-09-2026, 11:10 AM
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