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I wonder if anyone has information whether SeqStudio cathode buffer is the same as other running /cathode buffers for earlier ABI CE sequencers. In other words, can 10x running buffers for ABI CE sequencers available on the market can be used as SeqStuido cathode buffer?
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You can try it (especially with the used cartridge), but first I would measure the conductivity/pH of the ready cathode/anode buffer solution, than dillute the ABI CE buffer to the same ionic strength as new instrument ones. The buffering capacity of universal buffer is lower, than specifically made anode/cathode ones, but by how much, a test titration by acid/base can tell you. -
I am using ABI3500 for capillary fragment analysis, Can I just refill the cathode and anode buffer instead of changing them every time to make it cost effective?
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Hi there,
Any one use the product of Nimagen (Shop - NimaGen.com | Innovators in DNA Sequencing Technologies - NimaGen), they offer buffer for Seqstudio, has anyone use?Last edited by ahs810; 05-20-2025, 11:33 PM.Comment
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Hi there,
i have an issue, we purchased SeqStudio in 2021, problem is it often hang, 1st run in majority sizing issue (same sample in 2nd injection has data peaks & sized), contact support but no use. do anyone face the same issue?Comment
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Data variability is still an issue in sequencing technologies despite the advances in reproducibility and accuracy of these platforms. But the problem does not originate in the sequencing itself, but in the previous steps, before the sample reaches the sequencer.
The first step is collection, followed by preservation and sample preparation for analysis. Most scientists overlook those steps, but not being careful might just be skewing the experiment’s results.
...06-02-2026, 10:05 AM -
With the launch of new single-cell sequencing platforms in 2026, the field stands at an exciting inflection point. This article surveys the most impactful advances in the field and discusses how they’re reshaping research in cancer, immunology, and beyond.
Introduction
Single-cell sequencing technologies have undergone remarkable advances over the past decade, transitioning from low-throughput experimental approaches to highly scalable platforms capable of...05-22-2026, 06:42 AM
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