Hey all,
I've only ever looked at Illumina data, and we are being given exome data done with SOLiD sequencing. I am curious as to opinions regarding the optimal way to align this data. I figure once I get it into SAM format I can do what I normally do. Would NovoalignCS be a good option? I do not have a licensed version but I am not in a rush and can probably get by with the free downloadable version. Any other opinions? This is a one time thing to my knowledge so I just want to find something that will work and implement: knowing all of the caveats of each method is not important to me in this case. Thanks a bunch!
I've only ever looked at Illumina data, and we are being given exome data done with SOLiD sequencing. I am curious as to opinions regarding the optimal way to align this data. I figure once I get it into SAM format I can do what I normally do. Would NovoalignCS be a good option? I do not have a licensed version but I am not in a rush and can probably get by with the free downloadable version. Any other opinions? This is a one time thing to my knowledge so I just want to find something that will work and implement: knowing all of the caveats of each method is not important to me in this case. Thanks a bunch!
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