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Has anyone generated a Transcriptome Reference Genome on the 454 and then used it as a ref genome for a SOLiD transcriptome run?
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We have done this. Sort of. In principle it should work fine. But in the case we did it, the investigators were looking at small RNAs on the SOLiD, so little can be drawn as to the likely success of the method for SWTAK.Originally posted by DNADEB View Post
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Phillip
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The sequencing world is rapidly changing due to declining costs, enhanced accuracies, and the advent of newer, cutting-edge instruments. Equally important to these developments are improvements in sequencing analysis, a process that converts vast amounts of raw data into a comprehensible and meaningful form. This complex task requires expertise and the right analysis tools. In this article, we highlight the progress and innovation in sequencing analysis by reviewing several of the...05-06-2024, 07:48 AM -
The field of epigenetics has traditionally concentrated more on DNA and how changes like methylation and phosphorylation of histones impact gene expression and regulation. However, our increased understanding of RNA modifications and their importance in cellular processes has led to a rise in epitranscriptomics research. “Epitranscriptomics brings together the concepts of epigenetics and gene expression,” explained Adrien Leger, PhD, Principal Research Scientist...04-22-2024, 07:01 AM
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