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  • NextGenSeq
    Senior Member
    • Apr 2009
    • 482

    #1

    SOLiD-4 3K Genome?

    Life Technologies Brings Genomic Sequencing Closer to the Clinic

    Company announces SOLiD™ 4 System, delivering industry’s most cost effective, highest quality genome for $6,000, reduced to $3,000 by end of 2010 with SOLiD™ 4hq upgrade



    CARLSBAD, Calif.--(BUSINESS WIRE)--Life Technologies Corporation (NASDAQ:LIFE), a provider of innovative life science solutions, today announced a series of investments and new technologies designed to extend the use of sequencing in the research arena and make it more relevant for physicians.

    “This system is another example of why the Applied Biosystems brand has been synonymous with cutting edge sequencing technology for more than two decades”

    The company introduced the Applied Biosystems SOLiD™ 4 Sequencing System, the most advanced next-generation genomic analysis sequencing system on the market, generating up to 100 gigabases of mappable sequence data per run at a cost of $6,000 per genome. The system, which leverages proprietary advances in sequencing chemistry, will be available as an upgrade for all SOLiD installations in the first quarter of 2010. The company also announced that in the second half of the year, the SOLiD 4 System can be upgraded with the SOLiD 4hq package, which will generate up to 300 gigabases of mappable sequence data per run and deliver unprecedented accuracy of 99.99 percent, enabling customers to sequence the highest quality whole genome for a cost of $3,000.

    Concurrent with the launch of the SOLiD 4 System, researchers will also be able to reduce overall sequencing costs by automating their workflow through the introduction of the Applied Biosystems EZ Bead™ System. The EZ Bead System dramatically improves the efficiency of sample preparation and reduces hands-on and turnaround time by as much as 90 percent.

    "For sequencing to transition into a clinical diagnostic assay for conditions such as cancer, cardiovascular disease, and autism, it needs to be precise, reproducible and cost effective. SOLiD 4 is the first sequencing system to combine these attributes, promising to impact research and diagnostic applications," said Dr. Stephen Scherer, Director of the University of Toronto McLaughlin Centre and the Toronto Centre for Applied Genomics, and Senior Scientist at The Hospital for Sick Children.

    “This system is another example of why the Applied Biosystems brand has been synonymous with cutting edge sequencing technology for more than two decades,” said Gregory T. Lucier, Chairman and Chief Executive Officer of Life Technologies. “We remain committed to our customers, the SOLiD platform, and its current and future potential to help advance research that will ultimately revolutionize the practice of medicine.”

    The SOLiD 4 System represents Life Technologies’ latest offering in the sequencing market. The company is the leading provider of instruments across the sequencing spectrum, including the recently launched 3500 and 3500Dx Series Genetic Analyzers and other gold standard technologies in capillary electrophoresis sequencing. For more information on the SOLiD™ 4 Sequencing System, visit www.appliedbiosystems.com/solid4.

    Life Technologies also announced today that it will dedicate approximately $100 million over the next three years to address the challenge of bioinformatics – the analysis and interpretation of the vast amounts of data generated by whole genome sequencing. As a first step, the company announced the introduction of BioScope™, an appliance- or cloud-enabled software solution that decreases analysis time by 80 percent, enables industry leading SNP detection and transcriptome analysis, and allows researchers to export mappable sequence data into a standardized base sequence format. Moving forward, Life Technologies will also invest in improving the archiving, analysis and communication of sequencing information to help drive the adoption of genomics in both research and medicine.

  • skycreative
    Member
    • Jan 2010
    • 33

    #2
    I have receive the ppt

    Comment

    • pmiguel
      Senior Member
      • Aug 2008
      • 2328

      #3
      Originally posted by NextGenSeq View Post
      Life Technologies Brings Genomic Sequencing Closer to the Clinic

      Company announces SOLiD™ 4 System, delivering industry’s most cost effective, highest quality genome for $6,000, reduced to $3,000 by end of 2010 with SOLiD™ 4hq upgrade

      The email I got from Applied Biosystems estimated the current "cost" of a human genome sequence at $22,000 (version 3+ chemistry). Current cost of the chemistry/consumables alone for a 2 flow cell run (mate pair 50 base tags) is around $17,000. Seems like AB will have to drastically reduce costs for these to reach $6000 for a genome.

      I also wonder how much of the savings relies on purchasing the "EasyBead" system.

      --
      Phillip

      Comment

      • snetmcom
        Senior Member
        • Oct 2008
        • 159

        #4
        must have EZ bead. and the rest is simply more density with v4 + higher mapping numbers.

        Comment

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