sequence error detection in color space reads

[holywoool]

hi,everyone!

It is said that we are able to detect sequence error when coping with reads in color space var di-base encode methord.And this is true.

But if a sequence error site has a high QUAL value,then can we make a conclusion that this is a sequence error site? If so,does it sound of some controdiction?

What I am confused is that whether we regardless its QUAL value while detecting sequence error ?

Thanks