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  • bdilkes
    Junior Member
    • Dec 2009
    • 1

    #1

    AB inversion score method

    Does anyone know how the AB Inversion scores are calculated?
    The documentation states that the inversion score is the the harmonic mean of the breakpoint scores. The two breakpoint scores are derived (somehow) by the coverage of reads at each end of the putative breakpoint.

    Questions that come to mind:
    What kind of coverage generates what kind of scores? Are mates/PE that return normal (non-inverted) alignments considered as well?

    -BD
  • westerman
    Rick Westerman
    • Jun 2008
    • 1104

    #2
    I asked the question at the recent Bioscope webinar. Answers from the presenter were (1) don't know about the coverage and (2) yes, normal mates/PE alignments are considered.

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