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  • The Clinical Partner Program

    Exome Sequencing utilizes DNA-enrichment methods and massively parallel nucleotide sequencing to identify protein-coding variants in the genome. Together with growing public databases of known variants, exome sequencing allows for identification of genetic mutations and risk factors in samples that were deemed insufficiently informative for previous genetic studies. Not only does exome sequencing enable identification of mutations in families that were undetectable with linkage disequilibrium and positional cloning methods, but is also more rapid and less expensive. The use of exome sequencing has been successful in the characterization of many rare diseases.

    EdgeBio’s CLIA Exome Test is now available for clinical laboratories to incorporate into their current testing menu. With access to EdgeBio’s marketing and support, your lab will be empowered to offer cutting edge molecular testing to better serve your patient population. The CLIA Exome is a next generation sequencing test, conducted on the Illumina HiSeq 2000.
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  • seqadmin
    Exploring the Dynamics of the Tumor Microenvironment
    by seqadmin




    The complexity of cancer is clearly demonstrated in the diverse ecosystem of the tumor microenvironment (TME). The TME is made up of numerous cell types and its development begins with the changes that happen during oncogenesis. “Genomic mutations, copy number changes, epigenetic alterations, and alternative gene expression occur to varying degrees within the affected tumor cells,” explained Andrea O’Hara, Ph.D., Strategic Technical Specialist at Azenta. “As...
    07-08-2024, 03:19 PM
  • seqadmin
    Exploring Human Diversity Through Large-Scale Omics
    by seqadmin


    In 2003, researchers from the Human Genome Project (HGP) announced the most comprehensive genome to date1. Although the genome wasn’t fully completed until nearly 20 years later2, numerous large-scale projects, such as the International HapMap Project and 1000 Genomes Project, continued the HGP's work, capturing extensive variation and genomic diversity within humans. Recently, newer initiatives have significantly increased in scale and expanded beyond genomics, offering a more detailed...
    06-25-2024, 06:43 AM

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