Caliper GX

[BTS]

Greetings,

We're looking into purchasing a Caliper GX I or II. It's application would be mainly as a substitute to manual gel running but would also be used in some Next Gen library prep steps. Does anyone have any experience with these instruments and how well they work? Thanks in advance.

[TonyBrooks]

Have you ever looked for a <gizmo> from <company>?
This one is full automated and has much lower sample costs.
We are very happy with it.

I don't think the Fragment Analyzer has the ability to size select like the Calipers do. If you contact Caliper, we found them open to coming in a demo-ing in the lab on a few of your samples.

[ECO]

Removed nightfly's post and edited the quote as he was clearly posting an advertisement. Apologies for not catching it faster.

[454newbie]

We have been using a caliper GX for the last 18 months, mainly for routine analysis of PCR products and sequencing libraries. Performance in our hands is basically equivalent to the Agilent bioanalyzer, but with the advantage of throughput. We still use the bioanalyzer for experiments with <24 samples, and for high-sensitivity apps. We had a few problems with the machine initially, but these were fixed quickly. It now runs pretty much solidly 3-4 days a week, and has done without problem for at least 9 months.
hope this helps