Hi all, just wondering where you all would make the cutoff between short nucleosome-free regions and those included in a mononucleosome when looking at a High Sens Bioanalyzer trace? Attaching example where I assume the several peaks in the 100-175bp range, before the main ~200bp (mono?) peak, are nucleosome-free regions? Let me know what you all think, thanks!
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The field of epigenetics has traditionally concentrated more on DNA and how changes like methylation and phosphorylation of histones impact gene expression and regulation. However, our increased understanding of RNA modifications and their importance in cellular processes has led to a rise in epitranscriptomics research. “Epitranscriptomics brings together the concepts of epigenetics and gene expression,” explained Adrien Leger, PhD, Principal Research Scientist...-
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