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Anyone got any useful advice for what to do with extra DNA 1000 chips for the Bioanalyzer? We've got at least 3 dozen extra collecting in our drawers. What's everyone do with their extras?
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If you are using the BA for High Sensitivity assays still, you can buy High Sensitivity reagents and use them with the DNA 1000 chips. You just need to load the chip according to the High Sensitivity protocol and disregard the well labels on the DNA 1000 chip (ladder will go in the well that is labeled sample 12 and gel dye matrix in the well for the ladder).Josh Kinman -
To expand on this a little, it appears that all Bioanalyzer DNA and RNA chips are the same chip, just with a different sticker.Originally posted by jdk787 View PostComment
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That's super useful! Thanks, I'll be sure to start doing that.Comment
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Thank you jdk787 & kerplunk412! Very helpful!SeqDavisComment
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I’m not a sequencing expert. I’m a purification scientist who uses NGS to evaluate workflows my group develops. With this perspective, we think about the sample first and the NGS workflow second. The sequencer is an exceptionally honest reporter, but it can only report on what you give it, so whether you get clean, interpretable data from an NGS workflow is largely determined before you begin.
Here are nine questions we think about, in roughly the order they matter, before...06-18-2026, 07:11 AM -
Data variability is still an issue in sequencing technologies despite the advances in reproducibility and accuracy of these platforms. But the problem does not originate in the sequencing itself, but in the previous steps, before the sample reaches the sequencer.
The first step is collection, followed by preservation and sample preparation for analysis. Most scientists overlook those steps, but not being careful might just be skewing the experiment’s results.
...06-02-2026, 10:05 AM
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