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  • eleven
    Junior Member
    • Jan 2013
    • 9

    #1

    minimum and maximum CNV size by Read Depth?

    Hello! everyone.

    Read depth (RD) is a good method to detect CNV. Generally, CNV size by RD is not large as far as I know, also depends on pre-selected bin size such as 100bp or 500bp. So has someone known RD methods very well and what is the minimum and maximum CNV length approximately?

    Thanks a millionaire
  • JackieBadger
    Senior Member
    • Mar 2009
    • 385

    #2
    I am not sure if you are using the correct terminology or explaining your question very clearly. CNV relates to the estimated copy number of genes.... when alleles are indistinguishable in sequence at duplicated loci, RD is used to estimate the CNV based on sequence depth i.e. the number of sequences is some quantification of the number of loci. Sequence length is not used as a measure of CNV.

    Are you asking what are the best method to detect CNV using RD?
    If so..it is a burgeoning field.

    Comment

    • eleven
      Junior Member
      • Jan 2013
      • 9

      #3
      sorry for replaying you so late! I may be confused about conception, so thank you!

      Comment

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