Unconfigured Ad

Collapse
X
 
  • Time
  • Show
Clear All
new posts
  • eleven
    Junior Member
    • Jan 2013
    • 9

    #1

    minimum and maximum CNV size by Read Depth?

    Hello! everyone.

    Read depth (RD) is a good method to detect CNV. Generally, CNV size by RD is not large as far as I know, also depends on pre-selected bin size such as 100bp or 500bp. So has someone known RD methods very well and what is the minimum and maximum CNV length approximately?

    Thanks a millionaire
  • JackieBadger
    Senior Member
    • Mar 2009
    • 385

    #2
    I am not sure if you are using the correct terminology or explaining your question very clearly. CNV relates to the estimated copy number of genes.... when alleles are indistinguishable in sequence at duplicated loci, RD is used to estimate the CNV based on sequence depth i.e. the number of sequences is some quantification of the number of loci. Sequence length is not used as a measure of CNV.

    Are you asking what are the best method to detect CNV using RD?
    If so..it is a burgeoning field.

    Comment

    • eleven
      Junior Member
      • Jan 2013
      • 9

      #3
      sorry for replaying you so late! I may be confused about conception, so thank you!

      Comment

      Latest Articles

      Collapse

      • SEQadmin2
        How Immunogenomics Decodes Immunity’s Genetic Blueprint
        by SEQadmin2




        The immune system’s power comes from its genetic diversity, allowing myriad threats to be neutralized through first recognizing foreign antigens. That diversity is also what makes the immune system so difficult to study. Recent advances in sequencing technology and computational biology, however, are giving researchers new tools to understand immune responses and immune-related diseases in greater detail.

        This convergence of genetics, immunology, and computation...
        Today, 05:41 AM
      • SEQadmin2
        Beyond CRISPR/Cas9: Understand, Choose, and Use the Right Genome Editing Tool
        by SEQadmin2



        CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).

        Despite this, “CRISPR helped turn genome editing from a specialized technique into
        ...
        07-31-2026, 11:01 AM

      ad_right_rmr

      Collapse

      News

      Collapse

      Topics Statistics Last Post
      Started by SEQadmin2, 08-24-2026, 10:32 AM
      0 responses
      39 views
      0 reactions
      Last Post SEQadmin2  
      Started by SEQadmin2, 08-20-2026, 11:17 AM
      0 responses
      45 views
      0 reactions
      Last Post SEQadmin2  
      Started by SEQadmin2, 08-18-2026, 10:05 AM
      0 responses
      51 views
      0 reactions
      Last Post SEQadmin2  
      Started by SEQadmin2, 08-13-2026, 12:22 PM
      0 responses
      49 views
      0 reactions
      Last Post SEQadmin2  
      Working...