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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,627 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
684,232 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by Shaq, 07-10-2013, 05:16 AM
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2 responses
4,077 views
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by Shaq
07-10-2013, 06:40 AM
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Started by IHU, 07-10-2013, 05:55 AM
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0 responses
1,876 views
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by IHU
07-10-2013, 05:55 AM
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Started by tdoniger, 02-14-2013, 01:48 AM
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6 responses
5,190 views
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by tdoniger
07-10-2013, 05:19 AM
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Started by hiren, 07-10-2013, 04:53 AM
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0 responses
2,307 views
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by hiren
07-10-2013, 04:53 AM
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Started by dietmar13, 07-10-2013, 03:44 AM
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0 responses
920 views
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by dietmar13
07-10-2013, 03:44 AM
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Started by gen2prot, 07-09-2013, 01:02 AM
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4 responses
2,403 views
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by gen2prot
07-10-2013, 02:03 AM
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Started by Kennels, 07-09-2013, 07:00 PM
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0 responses
1,310 views
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by Kennels
07-09-2013, 07:00 PM
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Started by IsmailM, 07-09-2013, 02:27 PM
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0 responses
1,129 views
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by IsmailM
07-09-2013, 02:27 PM
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Started by zjrouc, 07-06-2013, 01:27 PM
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8 responses
2,748 views
0 reactions
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by Wallysb01
07-09-2013, 01:35 PM
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Started by Heisman, 07-09-2013, 11:02 AM
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2 responses
12,460 views
0 reactions
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Last Post
by Heisman
07-09-2013, 01:06 PM
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by SEQadmin2
Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...-
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by SEQadmin2
CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...-
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by SEQadmin2
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...-
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07-20-2026, 11:48 AM -
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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07-09-2026, 11:10 AM -
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Started by SEQadmin2, Yesterday, 02:55 AM
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0 responses
9 views
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by SEQadmin2
Yesterday, 02:55 AM
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Started by SEQadmin2, 07-24-2026, 12:17 PM
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0 responses
12 views
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by SEQadmin2
07-24-2026, 12:17 PM
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Started by SEQadmin2, 07-23-2026, 11:41 AM
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12 views
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by SEQadmin2
07-23-2026, 11:41 AM
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