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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,669 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
684,584 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by foxriverlin, 04-25-2013, 08:32 AM
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0 responses
1,125 views
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by foxriverlin
04-25-2013, 08:32 AM
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Started by empyrean, 04-25-2013, 07:05 AM
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0 responses
1,278 views
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by empyrean
04-25-2013, 07:05 AM
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Started by jmc200, 04-25-2013, 05:32 AM
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1,234 views
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by jmc200
04-25-2013, 05:32 AM
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Started by jkl, 04-25-2013, 02:54 AM
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1,452 views
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by jkl
04-25-2013, 02:54 AM
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Started by benjamin01, 04-24-2013, 11:35 PM
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0 responses
2,133 views
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by benjamin01
04-24-2013, 11:35 PM
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Started by adaptivegenome, 06-12-2012, 12:38 PM
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9 responses
6,071 views
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by kbradnam
04-24-2013, 11:08 PM
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Started by SEQquestions, 04-21-2013, 11:50 PM
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1 response
1,299 views
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by SEQquestions
04-24-2013, 10:44 PM
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Started by Nico86, 04-24-2013, 01:17 PM
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0 responses
2,438 views
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by Nico86
04-24-2013, 01:17 PM
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Started by dGho, 04-24-2013, 07:06 AM
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2 responses
2,184 views
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by dGho
04-24-2013, 10:46 AM
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Started by Jonny_D, 04-20-2013, 09:57 AM
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7 responses
2,110 views
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Last Post
by AlexReynolds
04-24-2013, 10:08 AM
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by SEQadmin2
Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...-
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07-31-2026, 07:00 AM -
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CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...-
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07-31-2026, 11:01 AM -
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by SEQadmin2
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...-
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07-20-2026, 11:48 AM -
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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07-09-2026, 11:10 AM -
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Started by SEQadmin2, Today, 07:41 AM
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9 views
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by SEQadmin2
Today, 07:41 AM
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Started by SEQadmin2, 08-03-2026, 10:13 AM
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25 views
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by SEQadmin2
08-03-2026, 10:13 AM
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Started by SEQadmin2, 07-31-2026, 02:55 AM
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38 views
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by SEQadmin2
07-31-2026, 02:55 AM
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