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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,619 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
684,184 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by Jonathan87, 01-18-2013, 02:39 AM
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0 responses
1,985 views
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by Jonathan87
01-18-2013, 02:39 AM
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Started by oxydeepu, 05-01-2012, 10:08 PM
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3 responses
2,421 views
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by soban
01-18-2013, 01:42 AM
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Started by Fred13, 12-09-2009, 07:24 AM
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5 responses
5,639 views
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by Fred13
01-18-2013, 01:39 AM
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Started by bharat_iyengar, 01-18-2013, 01:38 AM
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0 responses
2,103 views
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tophat (or tophat-fusion) v2.0.6 error on: Joining segment hits (long_spanning_reads)
by AndrewUzilov
Started by AndrewUzilov, 12-07-2012, 08:26 AM
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6 responses
4,499 views
0 reactions
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Last Post
by RocheKermit
01-18-2013, 12:25 AM
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Started by papori, 12-04-2012, 06:19 AM
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1 response
1,674 views
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by pengchy
01-17-2013, 10:04 PM
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Started by ajthomas, 01-16-2013, 12:01 PM
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7 responses
1,702 views
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by ajthomas
01-17-2013, 04:25 PM
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Started by NBlackburn, 01-14-2013, 04:53 PM
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2 responses
2,758 views
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by NBlackburn
01-17-2013, 04:12 PM
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Started by dray, 07-13-2012, 05:32 AM
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4 responses
1,675 views
0 reactions
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by crusoe
01-17-2013, 02:43 PM
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Started by yjx1217, 11-18-2011, 03:06 PM
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2 responses
3,527 views
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Last Post
by yjx1217
01-17-2013, 02:11 PM
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Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...-
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CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...-
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by SEQadmin2
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...-
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07-20-2026, 11:48 AM -
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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07-09-2026, 11:10 AM -
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Started by SEQadmin2, Today, 02:55 AM
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6 views
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by SEQadmin2
Today, 02:55 AM
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Started by SEQadmin2, 07-24-2026, 12:17 PM
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by SEQadmin2
07-24-2026, 12:17 PM
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Started by SEQadmin2, 07-23-2026, 11:41 AM
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by SEQadmin2
07-23-2026, 11:41 AM
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