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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,717 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
685,540 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by mortonm33, 07-18-2012, 08:30 AM
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4 responses
4,519 views
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by rnaNGS
11-21-2012, 09:28 PM
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Started by czc, 11-20-2012, 11:18 PM
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4 responses
6,598 views
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by czc
11-21-2012, 05:06 PM
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Started by abh, 11-21-2012, 10:06 AM
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1 response
11,357 views
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by dpryan
11-21-2012, 10:59 AM
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Started by angieant, 11-21-2012, 08:58 AM
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0 responses
1,489 views
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by angieant
11-21-2012, 08:58 AM
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Started by erichpeterson, 11-21-2012, 06:51 AM
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2 responses
2,447 views
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Started by ssn4ssn, 11-21-2012, 07:28 AM
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0 responses
1,715 views
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by ssn4ssn
11-21-2012, 07:28 AM
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Started by stylz2k, 11-21-2012, 01:02 AM
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2 responses
1,712 views
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by stylz2k
11-21-2012, 04:12 AM
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Started by bob-loblaw, 11-21-2012, 03:03 AM
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0 responses
1,348 views
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by bob-loblaw
11-21-2012, 03:03 AM
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Started by SHeaph, 11-20-2012, 07:52 AM
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5 responses
2,989 views
0 reactions
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by dpryan
11-21-2012, 02:05 AM
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Started by blankenberg, 03-29-2010, 12:25 PM
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6 responses
18,479 views
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by vinhha
11-21-2012, 12:59 AM
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by SEQadmin2
Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...-
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07-31-2026, 07:00 AM -
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by SEQadmin2
CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...-
Channel: Articles
07-31-2026, 11:01 AM -
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by SEQadmin2
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...-
Channel: Articles
07-20-2026, 11:48 AM -
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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Channel: Articles
07-09-2026, 11:10 AM -
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Started by SEQadmin2, 08-20-2026, 11:17 AM
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0 responses
17 views
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by SEQadmin2
08-20-2026, 11:17 AM
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Started by SEQadmin2, 08-18-2026, 10:05 AM
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0 responses
26 views
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by SEQadmin2
08-18-2026, 10:05 AM
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Started by SEQadmin2, 08-13-2026, 12:22 PM
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0 responses
42 views
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by SEQadmin2
08-13-2026, 12:22 PM
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