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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,705 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
685,376 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by thsuk1, 08-26-2010, 05:13 AM
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6 responses
15,067 views
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by lh3
08-27-2010, 08:54 AM
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Started by Niraks, 08-26-2010, 05:52 AM
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2 responses
2,045 views
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by lh3
08-27-2010, 08:36 AM
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Started by Nicolas902, 03-23-2010, 03:08 AM
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5 responses
4,341 views
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by anecsulea
08-27-2010, 08:02 AM
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Started by MatthewVC, 06-26-2010, 09:18 AM
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1 response
1,682 views
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by maf
08-27-2010, 05:17 AM
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Started by zwzhu, 08-27-2010, 04:46 AM
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0 responses
2,731 views
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by zwzhu
08-27-2010, 04:46 AM
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Started by brentp, 08-26-2010, 08:27 AM
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2 responses
2,698 views
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by simonandrews
08-27-2010, 04:08 AM
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Started by rahul.m.dhodapkar, 08-04-2010, 10:12 AM
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17 responses
4,552 views
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Started by kathrin, 08-25-2010, 12:28 AM
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4 responses
5,232 views
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by mattanswers
08-26-2010, 12:23 PM
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Started by asiangg, 08-24-2010, 07:46 AM
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11 responses
19,233 views
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by jwfoley
08-26-2010, 11:10 AM
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Started by asiangg, 08-24-2010, 07:33 AM
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3 responses
2,995 views
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by asiangg
08-26-2010, 05:31 AM
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by SEQadmin2
Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...-
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07-31-2026, 07:00 AM -
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by SEQadmin2
CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...-
Channel: Articles
07-31-2026, 11:01 AM -
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by SEQadmin2
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...-
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07-20-2026, 11:48 AM -
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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Channel: Articles
07-09-2026, 11:10 AM -
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Started by SEQadmin2, Today, 11:17 AM
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5 views
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by SEQadmin2
Today, 11:17 AM
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Started by SEQadmin2, 08-18-2026, 10:05 AM
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15 views
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by SEQadmin2
08-18-2026, 10:05 AM
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Started by SEQadmin2, 08-13-2026, 12:22 PM
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by SEQadmin2
08-13-2026, 12:22 PM
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