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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,338 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
683,110 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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FINAL CALL: A Practical Introduction to NGS Data Analysis (February 01-03, 2023)
by ecSeq Bioinformatics
Started by ecSeq Bioinformatics, 01-24-2023, 01:35 AM
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0 responses
210 views
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Started by [email protected], 01-19-2023, 02:07 PM
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74 views
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Started by ale_hpc, 08-22-2022, 01:58 AM
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1 response
174 views
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by maxrempel
01-15-2023, 06:00 PM
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Started by kaoutar, 01-13-2023, 01:01 AM
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0 responses
148 views
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by kaoutar
01-13-2023, 01:01 AM
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Started by Haumich, 01-11-2023, 04:35 AM
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0 responses
161 views
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by Haumich
01-11-2023, 04:35 AM
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Started by Pol2021, 01-06-2023, 12:38 AM
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277 views
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by Pol2021
01-06-2023, 12:38 AM
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Started by ndsimons, 12-28-2022, 04:50 PM
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1 response
438 views
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by ndsimons
01-05-2023, 04:02 PM
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Started by josk, 12-15-2022, 07:20 AM
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199 views
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by josk
12-15-2022, 07:20 AM
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Started by woa, 12-10-2022, 10:12 AM
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124 views
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by woa
12-10-2022, 10:12 AM
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Started by OYA, 12-02-2022, 01:37 AM
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128 views
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by OYA
12-02-2022, 01:37 AM
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by SEQadmin2
Cancer survival rates have significantly increased in the last few decades in the United States, reaching a combined 70% 5-year survival rate by 2021. Behind this number, there are years of research to find new therapies, drug targets, and early detection methods. But there is one core challenge that keeps slowing down these advances, and it’s about drug resistance.
There is no single reason why many patients don’t respond to treatment as expected. Cancer is...-
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by GATTACATLove this - good data definitely starts from good input, and poor input can only give relatively poor data. I particularly like the mention of Nanodrop/absorbance based methods for quantification. It's such a toss up if you'll get an accurate reading or what amounts to a randomly generated number, and a lot of library/sequencing related issues can be traced back to poor quant.
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07-01-2026, 11:43 AM -
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by SEQadmin2
I’m not a sequencing expert. I’m a purification scientist who uses NGS to evaluate workflows my group develops. With this perspective, we think about the sample first and the NGS workflow second. The sequencer is an exceptionally honest reporter, but it can only report on what you give it, so whether you get clean, interpretable data from an NGS workflow is largely determined before you begin.
Here are nine questions we think about, in roughly the order they matter, before...-
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Started by SEQadmin2, Yesterday, 10:08 AM
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Yesterday, 10:08 AM
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Started by SEQadmin2, 07-07-2026, 11:05 AM
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07-07-2026, 11:05 AM
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Started by SEQadmin2, 07-02-2026, 11:08 AM
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07-02-2026, 11:08 AM
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