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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,715 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
685,523 views
1 reaction
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by ECO
12-25-2009, 06:45 PM
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Started by ngs_per, 03-29-2015, 11:55 PM
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0 responses
1,869 views
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by ngs_per
03-29-2015, 11:55 PM
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Started by greener, 12-27-2012, 05:45 PM
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1 response
3,164 views
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by mashbaugh
03-29-2015, 09:47 AM
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Started by hlyates, 03-27-2015, 06:11 AM
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1 response
2,653 views
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by maubp
03-29-2015, 09:18 AM
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Started by hylei, 03-29-2015, 05:18 AM
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0 responses
1,297 views
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by hylei
03-29-2015, 05:18 AM
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Started by a_mt, 11-16-2012, 11:39 PM
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3 responses
5,051 views
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by gerbarinov
03-29-2015, 01:23 AM
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Started by yueli, 03-28-2015, 07:03 AM
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2 responses
1,448 views
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by yueli
03-29-2015, 01:04 AM
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Started by student-t, 03-26-2015, 03:21 PM
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3 responses
1,945 views
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by tedwong
03-28-2015, 05:48 PM
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Started by bigs, 03-11-2009, 01:12 PM
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14 responses
8,148 views
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Started by pickledzebra, 03-27-2015, 04:21 PM
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0 responses
1,897 views
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by pickledzebra
03-27-2015, 04:21 PM
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Started by Golsheed, 03-27-2015, 11:04 AM
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0 responses
2,037 views
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by Golsheed
03-27-2015, 11:04 AM
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by SEQadmin2
Next-generation sequencing (NGS) is now central to outbreak investigations and antimicrobial resistance tracking. Through sophisticated...-
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07-31-2026, 07:00 AM -
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by SEQadmin2
CRISPR/Cas9 sparked the gene editing revolution for both research and therapeutics.1 But this system still showed severe issues that limited its applications. The most prominent were the heavy reliance on PAM sequences, delivery limitations, double-stranded breaks that prompt unintended edits and cell death, and editing inefficiency (both in targeting and in knock-in reliability).
Despite this, “CRISPR helped turn genome editing from a specialized technique into...-
Channel: Articles
07-31-2026, 11:01 AM -
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by SEQadmin2
Proteomics platforms are evolving rapidly, with advances in mass spectrometry and affinity-based approaches expanding what researchers can detect and at what scale. As the field moves toward deeper proteome coverage and clinical applications, scientists face an increasingly complex landscape of tools. This article will explore how researchers are navigating these choices to find the right platform for their work.
The systematic characterization of the human proteome has...-
Channel: Articles
07-20-2026, 11:48 AM -
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by SEQadmin2
Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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Channel: Articles
07-09-2026, 11:10 AM -
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Started by SEQadmin2, 08-20-2026, 11:17 AM
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15 views
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by SEQadmin2
08-20-2026, 11:17 AM
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Started by SEQadmin2, 08-18-2026, 10:05 AM
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23 views
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by SEQadmin2
08-18-2026, 10:05 AM
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Started by SEQadmin2, 08-13-2026, 12:22 PM
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42 views
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by SEQadmin2
08-13-2026, 12:22 PM
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