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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
683,178 views
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by ECO
12-25-2009, 06:45 PM
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Started by MeliBio, 03-12-2025, 01:53 AM
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1 response
164 views
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by MeliBio
03-12-2025, 01:53 AM
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Started by ecSeq Bioinformatics, 03-10-2025, 11:32 PM
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43 views
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Started by Edinburgher, 03-10-2025, 10:59 PM
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by Edinburgher
03-10-2025, 10:59 PM
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Started by SteveYost, 02-11-2025, 11:08 AM
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2 responses
628 views
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by SteveYost
03-03-2025, 04:31 AM
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Started by MeliBio, 02-26-2025, 03:04 AM
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93 views
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by MeliBio
02-26-2025, 03:04 AM
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Started by nivmuk, 02-18-2025, 03:30 AM
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248 views
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by nivmuk
02-18-2025, 03:30 AM
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Started by Genospect, 02-16-2025, 01:21 AM
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109 views
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by Genospect
02-16-2025, 01:21 AM
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Started by ag2024, 02-11-2025, 03:21 PM
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1 response
196 views
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by fchatonnet
02-12-2025, 02:16 AM
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Started by M.Askari, 01-29-2025, 07:58 AM
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2 responses
258 views
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by fchatonnet
02-12-2025, 02:03 AM
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Single-Cell RNA-Seq Data Analysis: A Practical Introduction (March 17-19, 2025 in Berlin, Germany)
by ecSeq Bioinformatics
Started by ecSeq Bioinformatics, 02-12-2025, 12:06 AM
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Genomics studies in neuroscience face a special challenge due to the brain’s complexity and scarcity of samples. Mapping changes in cell type and state using conventional next-generation sequencing methods remains challenging. Advances in technologies like single-cell sequencing, spatial transcriptomics, and long-read sequencing have opened the door to deeper studies of the brain and diseases like Alzheimer’s, amyotrophic lateral sclerosis (ALS), and schizophrenia.
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Cancer survival rates have significantly increased in the last few decades in the United States, reaching a combined 70% 5-year survival rate by 2021. Behind this number, there are years of research to find new therapies, drug targets, and early detection methods. But there is one core challenge that keeps slowing down these advances, and it’s about drug resistance.
There is no single reason why many patients don’t respond to treatment as expected. Cancer is...-
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by GATTACATLove this - good data definitely starts from good input, and poor input can only give relatively poor data. I particularly like the mention of Nanodrop/absorbance based methods for quantification. It's such a toss up if you'll get an accurate reading or what amounts to a randomly generated number, and a lot of library/sequencing related issues can be traced back to poor quant.
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07-01-2026, 11:43 AM -
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Started by SEQadmin2, Today, 10:04 AM
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Today, 10:04 AM
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Started by SEQadmin2, Yesterday, 10:08 AM
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Yesterday, 10:08 AM
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Started by SEQadmin2, 07-07-2026, 11:05 AM
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07-07-2026, 11:05 AM
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