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Discussion of next-gen sequencing related bioinformatics: resources, algorithms, open source efforts, etc
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Started by laura, 05-09-2011, 04:42 AM
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35 responses
107,344 views
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by laura
12-05-2013, 02:37 AM
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Started by sci_guy, 01-23-2008, 11:19 PM
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236 responses
683,128 views
1 reaction
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Last Post
by ECO
12-25-2009, 06:45 PM
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Started by NGS_New_User, 11-22-2013, 07:50 AM
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8 responses
5,226 views
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by sphil
12-12-2013, 05:47 AM
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core genome
by mmmm
Started by mmmm, 12-12-2013, 03:56 AM
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1 response
1,101 views
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by GenoMax
12-12-2013, 04:20 AM
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Started by rahul2909, 12-12-2013, 02:09 AM
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0 responses
1,456 views
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by rahul2909
12-12-2013, 02:09 AM
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Started by Mike DS, 12-11-2013, 06:45 PM
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0 responses
1,679 views
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by Mike DS
12-11-2013, 06:45 PM
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Started by verdeseq, 12-10-2013, 11:12 AM
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2 responses
2,155 views
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Last Post
by verdeseq
12-11-2013, 04:24 PM
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Started by KnowNothing2, 12-11-2013, 07:18 AM
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10 responses
3,473 views
0 reactions
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by dpryan
12-11-2013, 03:21 PM
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Started by 11xinqi, 12-11-2013, 12:49 PM
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0 responses
2,372 views
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by 11xinqi
12-11-2013, 12:49 PM
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Started by NicoBxl, 02-24-2011, 04:55 AM
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2 responses
2,030 views
0 reactions
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by bfantinatti
12-11-2013, 10:06 AM
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Started by raphael123, 12-11-2013, 08:39 AM
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2 responses
1,657 views
0 reactions
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by raphael123
12-11-2013, 10:03 AM
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Started by sc10021, 12-11-2013, 06:26 AM
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0 responses
1,638 views
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Last Post
by sc10021
12-11-2013, 06:26 AM
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by SEQadmin2
Cancer survival rates have significantly increased in the last few decades in the United States, reaching a combined 70% 5-year survival rate by 2021. Behind this number, there are years of research to find new therapies, drug targets, and early detection methods. But there is one core challenge that keeps slowing down these advances, and it’s about drug resistance.
There is no single reason why many patients don’t respond to treatment as expected. Cancer is...-
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by GATTACATLove this - good data definitely starts from good input, and poor input can only give relatively poor data. I particularly like the mention of Nanodrop/absorbance based methods for quantification. It's such a toss up if you'll get an accurate reading or what amounts to a randomly generated number, and a lot of library/sequencing related issues can be traced back to poor quant.
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07-01-2026, 11:43 AM -
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by SEQadmin2
I’m not a sequencing expert. I’m a purification scientist who uses NGS to evaluate workflows my group develops. With this perspective, we think about the sample first and the NGS workflow second. The sequencer is an exceptionally honest reporter, but it can only report on what you give it, so whether you get clean, interpretable data from an NGS workflow is largely determined before you begin.
Here are nine questions we think about, in roughly the order they matter, before...-
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Started by SEQadmin2, Yesterday, 10:08 AM
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by SEQadmin2
Yesterday, 10:08 AM
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Started by SEQadmin2, 07-07-2026, 11:05 AM
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by SEQadmin2
07-07-2026, 11:05 AM
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Started by SEQadmin2, 07-02-2026, 11:08 AM
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by SEQadmin2
07-02-2026, 11:08 AM
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